Human Recombinant ST2 Protein

With the continuous expansion of the ivd market and in ivd molecular diagnostics industry, we not only provide high-quality raw materials such as CMIT/MIT Preservation, IVD preservatives, monoclonal antibodies, and antigens for the diagnostic industry but also provide IVD test kits like Ebola test kit, HCV test kits, dengue test kit, etc.

ST2, also known as IL-1 R4 and T1, is an Interleukin-1 receptor family recombinant human protein that contributes to Th2 immune responses (1, 2). Soluble ST2(sST2) is a member of the interleukin 1(IL-1) receptor family existing in blood. And it has been already confirmed to have capacity of capturing IL-33, inhibiting IL-33/ST2 signal transferring, and rise significantly in mechanical overloading cardiac cells. As a result, soluble ST2 can be detected in the blood when heart failure or chronical heart failure exacerbation, or heart muscle can not expand and contract because of cicatrization caused by AMI.     

Specification Of Human Recombinant ST2 Protein

Source: E.coli

Purification: Affinity purified.

Concentration: 1.4mg/ml

Buffer: 10mMpbs, PH=7.4, 1mm EDTA,0.1% SKL,0.2%NaN3

Preservative: 0.2%NaN3

Storage & Shelf life: Store at -20°C for 3 years. Avoid multiple freeze/thaw cycles.

Application Of Human Recombinant ST2 Protein

Suitable for use as a standard in immunoassay, immunogen for antisera production, and tracer for iodination. Each laboratory should determine an optimum working titer for use in its particular application.